Visualization of local DNA unwinding by Mre11/Rad50/Nbs1 using single-molecule FRET

Brian Cannon; Jeffrey Kuhnlein; Soo Hyun Yang; Anita Cheng; Detlev Schindler; Jeremy M. Stark; Rick Russell; Tanya T. Paull

doi:10.1073/pnas.1309816110

Visualization of local DNA unwinding by Mre11/Rad50/Nbs1 using single-molecule FRET

Brian Cannon, Jeffrey Kuhnlein, Soo Hyun Yang, Anita Cheng, Detlev Schindler, Jeremy M. Stark, Rick Russell, Tanya T. Paull

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Proceedings of the National Academy of Sciences of the United States of America
Volume	110
Issue number	47
DOIs	https://doi.org/10.1073/pnas.1309816110
State	Published - Nov 19 2013
Externally published	Yes

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Biology
Molecular Biology

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10.1073/pnas.1309816110License: Unspecified

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@article{d70e6b9032ba47589c8c4d4bc5b0f393,

title = "Visualization of local DNA unwinding by Mre11/Rad50/Nbs1 using single-molecule FRET",

author = "Brian Cannon and Jeffrey Kuhnlein and Yang, {Soo Hyun} and Anita Cheng and Detlev Schindler and Stark, {Jeremy M.} and Rick Russell and Paull, {Tanya T.}",

note = "The Mre11/Rad50/Nbs1 (MRN) complex recognizes double-strand breaks in eukaryotic cells, initiating DNA repair and signaling cell cycle checkpoint arrest. Several enzymes are known to be stimulated at sites of breaks through the actions of MRN, including nucleases and the ATM protein kinase.",

year = "2013",

month = nov,

day = "19",

doi = "10.1073/pnas.1309816110",

language = "American English",

volume = "110",

journal = "Proceedings of the National Academy of Sciences of the United States of America",

number = "47",

}

TY - JOUR

T1 - Visualization of local DNA unwinding by Mre11/Rad50/Nbs1 using single-molecule FRET

AU - Cannon, Brian

AU - Kuhnlein, Jeffrey

AU - Yang, Soo Hyun

AU - Cheng, Anita

AU - Schindler, Detlev

AU - Stark, Jeremy M.

AU - Russell, Rick

AU - Paull, Tanya T.

N1 - The Mre11/Rad50/Nbs1 (MRN) complex recognizes double-strand breaks in eukaryotic cells, initiating DNA repair and signaling cell cycle checkpoint arrest. Several enzymes are known to be stimulated at sites of breaks through the actions of MRN, including nucleases and the ATM protein kinase.

PY - 2013/11/19

Y1 - 2013/11/19

UR - http://www.pnas.org/content/110/47/18868.long

U2 - 10.1073/pnas.1309816110

DO - 10.1073/pnas.1309816110

M3 - Article

VL - 110

JO - Proceedings of the National Academy of Sciences of the United States of America

JF - Proceedings of the National Academy of Sciences of the United States of America

IS - 47

ER -

Visualization of local DNA unwinding by Mre11/Rad50/Nbs1 using single-molecule FRET

Disciplines

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