The Multistage Antimalarial Compound Calxinin Perturbates P. falciparum Ca2+ Homeostasis by Targeting a Unique Ion Channel

Yash Gupta; Neha Sharma; Snigdha Singh; Jesus G. Romero; Vinoth Rajendran; Reagan M. Mogire; Mohammad Kashif; Jordan Beach; Walter Jeske; Poonam; Bernhards R. Ogutu; Stefan M. Kanzok; Hoseah M. Akala; Jennifer Legac; Philip J. Rosenthal; David J. Rademacher; Ravi Durvasula; Agam P. Singh; Brijesh Rathi; Prakasha Kempaiah

doi:10.3390/pharmaceutics14071371

The Multistage Antimalarial Compound Calxinin Perturbates P. falciparum Ca²⁺ Homeostasis by Targeting a Unique Ion Channel

Yash Gupta, Neha Sharma, Snigdha Singh, Jesus G. Romero, Vinoth Rajendran, Reagan M. Mogire, Mohammad Kashif, Jordan Beach, Walter Jeske, Poonam, Bernhards R. Ogutu, Stefan M. Kanzok, Hoseah M. Akala, Jennifer Legac, Philip J. Rosenthal, David J. Rademacher, Ravi Durvasula, Agam P. Singh, Brijesh Rathi, Prakasha Kempaiah

Department of Biology

Research output: Contribution to journal › Article › peer-review

Original language	English
Article number	1371
Journal	Pharmaceutics
Volume	14
Issue number	7
DOIs	https://doi.org/10.3390/pharmaceutics14071371
State	Published - Jul 2022

ASJC Scopus Subject Areas

Pharmaceutical Science

Keywords

Ca homeostasis
antimalarial
electron microscopy
field isolates
multistage activity
transient receptor potential mucolipin like channel

Access to Document

10.3390/pharmaceutics14071371

Cite this

Gupta, Y., Sharma, N., Singh, S., Romero, J. G., Rajendran, V., Mogire, R. M., Kashif, M., Beach, J., Jeske, W., Poonam, Ogutu, B. R., Kanzok, S. M., Akala, H. M., Legac, J., Rosenthal, P. J., Rademacher, D. J., Durvasula, R., Singh, A. P., Rathi, B., & Kempaiah, P. (2022). The Multistage Antimalarial Compound Calxinin Perturbates P. falciparum Ca²⁺ Homeostasis by Targeting a Unique Ion Channel. Pharmaceutics, 14(7), Article 1371. https://doi.org/10.3390/pharmaceutics14071371

Gupta, Y, Sharma, N, Singh, S, Romero, JG, Rajendran, V, Mogire, RM, Kashif, M, Beach, J, Jeske, W, Poonam, Ogutu, BR, Kanzok, SM, Akala, HM, Legac, J, Rosenthal, PJ, Rademacher, DJ, Durvasula, R, Singh, AP, Rathi, B & Kempaiah, P 2022, 'The Multistage Antimalarial Compound Calxinin Perturbates P. falciparum Ca²⁺ Homeostasis by Targeting a Unique Ion Channel', Pharmaceutics, vol. 14, no. 7, 1371. https://doi.org/10.3390/pharmaceutics14071371

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keywords = "Ca homeostasis, antimalarial, electron microscopy, field isolates, multistage activity, transient receptor potential mucolipin like channel",

author = "Yash Gupta and Neha Sharma and Snigdha Singh and Romero, \{Jesus G.\} and Vinoth Rajendran and Mogire, \{Reagan M.\} and Mohammad Kashif and Jordan Beach and Walter Jeske and Poonam and Ogutu, \{Bernhards R.\} and Kanzok, \{Stefan M.\} and Akala, \{Hoseah M.\} and Jennifer Legac and Rosenthal, \{Philip J.\} and Rademacher, \{David J.\} and Ravi Durvasula and Singh, \{Agam P.\} and Brijesh Rathi and Prakasha Kempaiah",

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AU - Romero, Jesus G.

AU - Rajendran, Vinoth

AU - Mogire, Reagan M.

AU - Kashif, Mohammad

AU - Beach, Jordan

AU - Jeske, Walter

AU - Poonam,

AU - Ogutu, Bernhards R.

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AU - Akala, Hoseah M.

AU - Legac, Jennifer

AU - Rosenthal, Philip J.

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KW - multistage activity

KW - transient receptor potential mucolipin like channel

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