Synthesis of Substituted 2-Amino-Cyclobutanones

Nicola Armoush; Preeti Syal; Daniel P. Becker

doi:10.1080/00397910801981110

Synthesis of Substituted 2-Amino-Cyclobutanones

Nicola Armoush, Preeti Syal, Daniel P. Becker

Department of Chemistry and Biochemistry

Loyola University Chicago

Research output: Contribution to journal › Article › peer-review

Abstract

A series of weakly nucleophilic nitrogen derivatives including carbamates, amides, sulfonamides, and anilines were reacted with 1,2-bis(trimethylsilyloxy)cyclobutene under acidic conditions to afford various substituted 2-aminocyclobutanone derivatives 3a–i in modest to excellent yields.

Original language	American English
Journal	Chemistry: Faculty Publications and Other Works
Volume	38
Issue number	11
DOIs	https://doi.org/10.1080/00397910801981110
State	Published - May 9 2008

Keywords

synthesis
2-Amino-Cyclobutanones

Disciplines

Chemistry

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title = "Synthesis of Substituted 2-Amino-Cyclobutanones",

abstract = " A series of weakly nucleophilic nitrogen derivatives including carbamates, amides, sulfonamides, and anilines were reacted with 1,2-bis(trimethylsilyloxy)cyclobutene under acidic conditions to afford various substituted 2-aminocyclobutanone derivatives 3a–i in modest to excellent yields.",

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AU - Syal, Preeti

AU - Becker, Daniel P.

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Y1 - 2008/5/9

N2 - A series of weakly nucleophilic nitrogen derivatives including carbamates, amides, sulfonamides, and anilines were reacted with 1,2-bis(trimethylsilyloxy)cyclobutene under acidic conditions to afford various substituted 2-aminocyclobutanone derivatives 3a–i in modest to excellent yields.

AB - A series of weakly nucleophilic nitrogen derivatives including carbamates, amides, sulfonamides, and anilines were reacted with 1,2-bis(trimethylsilyloxy)cyclobutene under acidic conditions to afford various substituted 2-aminocyclobutanone derivatives 3a–i in modest to excellent yields.

KW - synthesis

KW - 2-Amino-Cyclobutanones

UR - https://ecommons.luc.edu/chemistry_facpubs/26

U2 - 10.1080/00397910801981110

DO - 10.1080/00397910801981110

M3 - Article

VL - 38

JO - Chemistry: Faculty Publications and Other Works

JF - Chemistry: Faculty Publications and Other Works

IS - 11

ER -

Synthesis of Substituted 2-Amino-Cyclobutanones

Abstract

Keywords

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