Synthesis of Pyrazole-Based Inhibitors of the Bacterial Enzyme N-Succinyl-l,l-2,6-Diaminopimelic Acid Desuccinylase (DapE) as Potential Antibiotics

  • Thomas DiPuma
  • , Emma H. Kelley
  • , Teerana Thabthimthong
  • , Alayna Bland
  • , Katherine Konczak
  • , Katherine J. Torma
  • , Thahani S.Habeeb Mohammad
  • , Kenneth W. Olsen
  • , Daniel P. Becker

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Article number22
JournalInternational Journal of Molecular Sciences
Volume26
Issue number1
DOIs
StatePublished - Jan 2025
Externally publishedYes

ASJC Scopus Subject Areas

  • Catalysis
  • Molecular Biology
  • Spectroscopy
  • Computer Science Applications
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

Keywords

  • antibiotic
  • DapE
  • metalloenzyme
  • ninhydrin

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