Synthesis of Pyrazole-Based Inhibitors of the Bacterial Enzyme N-Succinyl-l,l-2,6-Diaminopimelic Acid Desuccinylase (DapE) as Potential Antibiotics

Thomas DiPuma, Emma H. Kelley, Teerana Thabthimthong, Alayna Bland, Katherine Konczak, Katherine J. Torma, Thahani S.Habeeb Mohammad, Kenneth W. Olsen, Daniel P. Becker

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Article number22
JournalInternational Journal of Molecular Sciences
Volume26
Issue number1
DOIs
StatePublished - Jan 2025
Externally publishedYes

ASJC Scopus Subject Areas

  • Catalysis
  • Molecular Biology
  • Spectroscopy
  • Computer Science Applications
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

Keywords

  • antibiotic
  • DapE
  • metalloenzyme
  • ninhydrin

Cite this