Synthesis and Activity of Selective MMP Inhibitors with an Aryl Backbone

Thomas Barta; Daniel P. Becker; Louis J. Bedell; Gary A. De Crescenzo

doi:10.1016/S0960-894X(00)00584-9

Synthesis and Activity of Selective MMP Inhibitors with an Aryl Backbone

Thomas Barta, Daniel P. Becker, Louis J. Bedell, Gary A. De Crescenzo

Department of Chemistry and Biochemistry

Research output: Contribution to journal › Article › peer-review

Abstract

A series of novel, MMP-1 sparing arylhydroxamate sulfonamides with activity against MMP-2 and -13 is described.

Original language	American English
Journal	Chemistry: Faculty Publications and Other Works
Volume	10
Issue number	24
DOIs	https://doi.org/10.1016/S0960-894X(00)00584-9
State	Published - Dec 18 2000

Keywords

aryl backbone
MMP inhibitors

Disciplines

Chemistry

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Cite this

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title = "Synthesis and Activity of Selective MMP Inhibitors with an Aryl Backbone",

abstract = " A series of novel, MMP-1 sparing arylhydroxamate sulfonamides with activity against MMP-2 and -13 is described.",

keywords = "aryl backbone, MMP inhibitors",

author = "Thomas Barta and Becker, {Daniel P.} and Bedell, {Louis J.} and {De Crescenzo}, {Gary A.}",

year = "2000",

month = dec,

day = "18",

doi = "10.1016/S0960-894X(00)00584-9",

language = "American English",

volume = "10",

journal = "Chemistry: Faculty Publications and Other Works",

number = "24",

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TY - JOUR

T1 - Synthesis and Activity of Selective MMP Inhibitors with an Aryl Backbone

AU - Barta, Thomas

AU - Becker, Daniel P.

AU - Bedell, Louis J.

AU - De Crescenzo, Gary A.

PY - 2000/12/18

Y1 - 2000/12/18

N2 - A series of novel, MMP-1 sparing arylhydroxamate sulfonamides with activity against MMP-2 and -13 is described.

AB - A series of novel, MMP-1 sparing arylhydroxamate sulfonamides with activity against MMP-2 and -13 is described.

KW - aryl backbone

KW - MMP inhibitors

UR - https://ecommons.luc.edu/chemistry_facpubs/18

U2 - 10.1016/S0960-894X(00)00584-9

DO - 10.1016/S0960-894X(00)00584-9

M3 - Article

VL - 10

JO - Chemistry: Faculty Publications and Other Works

JF - Chemistry: Faculty Publications and Other Works

IS - 24

ER -

Synthesis and Activity of Selective MMP Inhibitors with an Aryl Backbone

Abstract

Keywords

Disciplines

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