@article{140f5b8d80ae409aa0b167e31f3164cb,
title = "Substitution of the Thioredoxin System for Glutathione Reductase in Drosophila melanogaster",
author = "Kanzok, {Stefan M.} and Anke Fechner and Holger Bauer and Ulschmid, {Julia K.} and Hans-Michael M{\"u}ller and Jos{\'e} Botella-Munoz and Stephan Schneuwly and Schirmer, {R. Heiner} and Katja Becker",
note = "The disulfide reducing enzymes glutathione reductase and thioredoxin reductase are highly conserved among bacteria, fungi, worms, and mammals. These proteins maintain intracellular redox homeostasis to protect the organism from oxidative damage. Here we demonstrate the absence of glutathione reductase in Drosophila melanogaster , identify a new type of thioredoxin reductase, and provide evidence that a thioredoxin system supports GSSG reduction.",
year = "2001",
month = jan,
day = "26",
doi = "10.1126/science.291.5504.643",
language = "American English",
volume = "291",
journal = "Science",
issn = "1095-9203",
number = "5504",
}