Structural and Transient Kinetic Analyses Reveal the Dual Inhibition Modes of Human Ornithine Aminotransferase by (1S, 3S)-3-Amino-4-(Hexafluoropropan-2-Ylidenyl)-Cyclopentane-1-Carboxylic Acid (BCF3).

Dali Liu

Structural and Transient Kinetic Analyses Reveal the Dual Inhibition Modes of Human Ornithine Aminotransferase by (1S, 3S)-3-Amino-4-(Hexafluoropropan-2-Ylidenyl)-Cyclopentane-1-Carboxylic Acid (BCF3).

Department of Chemistry and Biochemistry

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	ACS Chemical Biology
State	Published - 2021

Disciplines

Biochemistry
Chemistry

Cite this

@article{e0d3d269aa7041fd8db43f700ab3c635,

title = "Structural and Transient Kinetic Analyses Reveal the Dual Inhibition Modes of Human Ornithine Aminotransferase by (1S, 3S)-3-Amino-4-(Hexafluoropropan-2-Ylidenyl)-Cyclopentane-1-Carboxylic Acid (BCF3).",

author = "Dali Liu",

note = "Hepatocellular carcinoma (HCC) is the most common form of liver cancer and the leading cause of death among people with cirrhosis. HCC is typically diagnosed in advanced stages when tumors are resistant to both radio- and chemotherapy. Human ornithine aminotransferase ( h OAT) is a pyridoxal-5' ...",

year = "2021",

language = "American English",

journal = "ACS Chemical Biology",

issn = "1554-8937",

}

TY - JOUR

T1 - Structural and Transient Kinetic Analyses Reveal the Dual Inhibition Modes of Human Ornithine Aminotransferase by (1S, 3S)-3-Amino-4-(Hexafluoropropan-2-Ylidenyl)-Cyclopentane-1-Carboxylic Acid (BCF3).

AU - Liu, Dali

N1 - Hepatocellular carcinoma (HCC) is the most common form of liver cancer and the leading cause of death among people with cirrhosis. HCC is typically diagnosed in advanced stages when tumors are resistant to both radio- and chemotherapy. Human ornithine aminotransferase ( h OAT) is a pyridoxal-5' ...

PY - 2021

Y1 - 2021

UR - https://pubmed.ncbi.nlm.nih.gov/33316155/

M3 - Article

SN - 1554-8937

JO - ACS Chemical Biology

JF - ACS Chemical Biology

ER -

Structural and Transient Kinetic Analyses Reveal the Dual Inhibition Modes of Human Ornithine Aminotransferase by (1S, 3S)-3-Amino-4-(Hexafluoropropan-2-Ylidenyl)-Cyclopentane-1-Carboxylic Acid (BCF3).

Disciplines

Other files and links

Cite this