Simulating the effect of DNA polymerase mutations on transition-state energetics and fidelity: Evaluating amino acid group contribution and allosteric coupling for ionized residues in human pol β

Yun Xiang; Peter Oelschlaeger; Jan Florián; Myron F. Goodman; Arieh Warshel

doi:10.1021/bi060147o

Simulating the effect of DNA polymerase mutations on transition-state energetics and fidelity: Evaluating amino acid group contribution and allosteric coupling for ionized residues in human pol β

Yun Xiang
, Peter Oelschlaeger
, Jan Florián
, Myron F. Goodman
, Arieh Warshel

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	7036-7048
Number of pages	13
Journal	Physics Faculty Research and Publications
Volume	45
Issue number	23
DOIs	https://doi.org/10.1021/bi060147o
State	Published - Jun 13 2006
Externally published	Yes

ASJC Scopus Subject Areas

Biochemistry

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10.1021/bi060147o

Cite this

Xiang, Y., Oelschlaeger, P., Florián, J., Goodman, M. F., & Warshel, A. (2006). Simulating the effect of DNA polymerase mutations on transition-state energetics and fidelity: Evaluating amino acid group contribution and allosteric coupling for ionized residues in human pol β. Physics Faculty Research and Publications, 45(23), 7036-7048. https://doi.org/10.1021/bi060147o

Simulating the effect of DNA polymerase mutations on transition-state energetics and fidelity: Evaluating amino acid group contribution and allosteric coupling for ionized residues in human pol β. / Xiang, Yun; Oelschlaeger, Peter; Florián, Jan et al.
In: Physics Faculty Research and Publications, Vol. 45, No. 23, 13.06.2006, p. 7036-7048.

Research output: Contribution to journal › Article › peer-review

Xiang, Y, Oelschlaeger, P, Florián, J, Goodman, MF & Warshel, A 2006, 'Simulating the effect of DNA polymerase mutations on transition-state energetics and fidelity: Evaluating amino acid group contribution and allosteric coupling for ionized residues in human pol β', Physics Faculty Research and Publications, vol. 45, no. 23, pp. 7036-7048. https://doi.org/10.1021/bi060147o

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Simulating the effect of DNA polymerase mutations on transition-state energetics and fidelity: Evaluating amino acid group contribution and allosteric coupling for ionized residues in human pol β

ASJC Scopus Subject Areas

Access to Document

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