Selective Targeting by a Mechanism-Based Inactivator against Pyridoxal 5′-Phosphate-Dependent Enzymes: Mechanisms of Inactivation and Alternative Turnover

Romila Mascarenhas; Hoang V. Le; Kenneth D. Clevenger; Helaina J. Lehrer; Dagmar Ringe; Neil L. Kelleher; Richard B. Silverman; Dali Liu

doi:10.1021/acs.biochem.7b00499

Selective Targeting by a Mechanism-Based Inactivator against Pyridoxal 5′-Phosphate-Dependent Enzymes: Mechanisms of Inactivation and Alternative Turnover

Romila Mascarenhas
, Hoang V. Le
, Kenneth D. Clevenger
, Helaina J. Lehrer
, Dagmar Ringe
, Neil L. Kelleher
, Richard B. Silverman
, Dali Liu

Department of Chemistry and Biochemistry

Loyola University Chicago
Northwestern University
Brandeis University

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Biochemistry
Volume	56
Issue number	37
DOIs	https://doi.org/10.1021/acs.biochem.7b00499
State	Published - Sep 19 2017

Disciplines

Molecular Biology
Biochemistry

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10.1021/acs.biochem.7b00499License: Unspecified

Cite this

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title = "Selective Targeting by a Mechanism-Based Inactivator against Pyridoxal 5′-Phosphate-Dependent Enzymes: Mechanisms of Inactivation and Alternative Turnover",

author = "Romila Mascarenhas and Le, \{Hoang V.\} and Clevenger, \{Kenneth D.\} and Lehrer, \{Helaina J.\} and Dagmar Ringe and Kelleher, \{Neil L.\} and Silverman, \{Richard B.\} and Dali Liu",

year = "2017",

month = sep,

day = "19",

doi = "10.1021/acs.biochem.7b00499",

language = "American English",

volume = "56",

journal = "Biochemistry",

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T1 - Selective Targeting by a Mechanism-Based Inactivator against Pyridoxal 5′-Phosphate-Dependent Enzymes: Mechanisms of Inactivation and Alternative Turnover

AU - Mascarenhas, Romila

AU - Le, Hoang V.

AU - Clevenger, Kenneth D.

AU - Lehrer, Helaina J.

AU - Ringe, Dagmar

AU - Kelleher, Neil L.

AU - Silverman, Richard B.

AU - Liu, Dali

PY - 2017/9/19

Y1 - 2017/9/19

UR - http://pubs.acs.org/doi/abs/10.1021/acs.biochem.7b00499

U2 - 10.1021/acs.biochem.7b00499

DO - 10.1021/acs.biochem.7b00499

M3 - Article

VL - 56

JO - Biochemistry

JF - Biochemistry

IS - 37

ER -

Selective Targeting by a Mechanism-Based Inactivator against Pyridoxal 5′-Phosphate-Dependent Enzymes: Mechanisms of Inactivation and Alternative Turnover

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