Selective Targeting by a Mechanism-Based Inactivator against Pyridoxal 5′-Phosphate-Dependent Enzymes: Mechanisms of Inactivation and Alternative Turnover

Romila Mascarenhas; Hoang V. Le; Kenneth D. Clevenger; Helaina J. Lehrer; Dagmar Ringe; Neil L. Kelleher; Richard B. Silverman; Dali Liu

doi:10.1021/acs.biochem.7b00499

Selective Targeting by a Mechanism-Based Inactivator against Pyridoxal 5′-Phosphate-Dependent Enzymes: Mechanisms of Inactivation and Alternative Turnover

Romila Mascarenhas, Hoang V. Le, Kenneth D. Clevenger, Helaina J. Lehrer, Dagmar Ringe, Neil L. Kelleher, Richard B. Silverman, Dali Liu

Department of Chemistry and Biochemistry

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Biochemistry
Volume	56
Issue number	37
DOIs	https://doi.org/10.1021/acs.biochem.7b00499
State	Published - Sep 19 2017

Disciplines

Molecular Biology
Biochemistry

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10.1021/acs.biochem.7b00499License: Unspecified

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title = "Selective Targeting by a Mechanism-Based Inactivator against Pyridoxal 5′-Phosphate-Dependent Enzymes: Mechanisms of Inactivation and Alternative Turnover",

author = "Romila Mascarenhas and Le, \{Hoang V.\} and Clevenger, \{Kenneth D.\} and Lehrer, \{Helaina J.\} and Dagmar Ringe and Kelleher, \{Neil L.\} and Silverman, \{Richard B.\} and Dali Liu",

year = "2017",

month = sep,

day = "19",

doi = "10.1021/acs.biochem.7b00499",

language = "American English",

volume = "56",

journal = "Biochemistry",

number = "37",

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T1 - Selective Targeting by a Mechanism-Based Inactivator against Pyridoxal 5′-Phosphate-Dependent Enzymes: Mechanisms of Inactivation and Alternative Turnover

AU - Mascarenhas, Romila

AU - Le, Hoang V.

AU - Clevenger, Kenneth D.

AU - Lehrer, Helaina J.

AU - Ringe, Dagmar

AU - Kelleher, Neil L.

AU - Silverman, Richard B.

AU - Liu, Dali

PY - 2017/9/19

Y1 - 2017/9/19

UR - http://pubs.acs.org/doi/abs/10.1021/acs.biochem.7b00499

U2 - 10.1021/acs.biochem.7b00499

DO - 10.1021/acs.biochem.7b00499

M3 - Article

VL - 56

JO - Biochemistry

JF - Biochemistry

IS - 37

ER -

Selective Targeting by a Mechanism-Based Inactivator against Pyridoxal 5′-Phosphate-Dependent Enzymes: Mechanisms of Inactivation and Alternative Turnover

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