RNA-seq analysis of chondrocyte transcriptome reveals genetic heterogeneity in LG/J and SM/J murine strains

Xin Duan; Lei Cai; Eric J. Schmidt; Jie Shen; Eric D. Tycksen; Regis O’Keefe; James M. Cheverud; Muhammad Farooq Rai

doi:10.1016/J.JOCA.2020.01.001

RNA-seq analysis of chondrocyte transcriptome reveals genetic heterogeneity in LG/J and SM/J murine strains

Xin Duan
, Lei Cai
, Eric J. Schmidt
, Jie Shen
, Eric D. Tycksen
, Regis O’Keefe
, James M. Cheverud
, Muhammad Farooq Rai

Department of Biology

Washington University in St. Louis
College of Health Sciences, Bahrain

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Osteoarthritis and Cartilage
Volume	28
Issue number	4
DOIs	https://doi.org/10.1016/J.JOCA.2020.01.001
State	Published - Apr 1 2020

Disciplines

Molecular Biology
Biology

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Cite this

@article{a83e52f73ec6499695499d7597bf0d17,

title = "RNA-seq analysis of chondrocyte transcriptome reveals genetic heterogeneity in LG/J and SM/J murine strains",

author = "Xin Duan and Lei Cai and Schmidt, \{Eric J.\} and Jie Shen and Tycksen, \{Eric D.\} and Regis O{\textquoteright}Keefe and Cheverud, \{James M.\} and Rai, \{Muhammad Farooq\}",

note = "Objective: To investigate the transcriptomic differences in chondrocytes obtained from LG/J (large, healer) and SM/J (small, non-healer) murine strains in an attempt to discern the molecular pathways implicated in cartilage regeneration and susceptibility to osteoarthritis (OA). Design: We performed RNA-sequencing on chondrocytes derived from LG/J (n = 16) and SM/J (n = 16) mice.",

year = "2020",

month = apr,

day = "1",

doi = "10.1016/J.JOCA.2020.01.001",

language = "American English",

volume = "28",

journal = "Osteoarthritis and Cartilage",

issn = "1522-9653",

number = "4",

}

TY - JOUR

T1 - RNA-seq analysis of chondrocyte transcriptome reveals genetic heterogeneity in LG/J and SM/J murine strains

AU - Duan, Xin

AU - Cai, Lei

AU - Schmidt, Eric J.

AU - Shen, Jie

AU - Tycksen, Eric D.

AU - O’Keefe, Regis

AU - Cheverud, James M.

AU - Rai, Muhammad Farooq

N1 - Objective: To investigate the transcriptomic differences in chondrocytes obtained from LG/J (large, healer) and SM/J (small, non-healer) murine strains in an attempt to discern the molecular pathways implicated in cartilage regeneration and susceptibility to osteoarthritis (OA). Design: We performed RNA-sequencing on chondrocytes derived from LG/J (n = 16) and SM/J (n = 16) mice.

PY - 2020/4/1

Y1 - 2020/4/1

UR - https://profiles.wustl.edu/en/publications/rna-seq-analysis-of-chondrocyte-transcriptome-reveals-genetic-het

U2 - 10.1016/J.JOCA.2020.01.001

DO - 10.1016/J.JOCA.2020.01.001

M3 - Article

SN - 1522-9653

VL - 28

JO - Osteoarthritis and Cartilage

JF - Osteoarthritis and Cartilage

IS - 4

ER -

RNA-seq analysis of chondrocyte transcriptome reveals genetic heterogeneity in LG/J and SM/J murine strains

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