Repurposing Lansoprazole and Posaconazole to treat leishmaniasis: Integration of in vitro testing, pharmacological corroboration, and mechanisms of action

Yash Gupta; Steven Goicoechea; Jesus G. Romero; Raman Mathur; Thomas R. Caulfield; Daniel P. Becker; Ravi Durvasula; Prakasha Kempaiah

doi:10.38212/2224-6614.3394

Repurposing Lansoprazole and Posaconazole to treat leishmaniasis: Integration of in vitro testing, pharmacological corroboration, and mechanisms of action

Yash Gupta, Steven Goicoechea, Jesus G. Romero, Raman Mathur, Thomas R. Caulfield, Daniel P. Becker, Ravi Durvasula, Prakasha Kempaiah

Research output: Contribution to journal › Article › peer-review

Original language	English
Article number	11
Pages (from-to)	128-149
Number of pages	22
Journal	Journal of Food and Drug Analysis
Volume	30
Issue number	1
DOIs	https://doi.org/10.38212/2224-6614.3394
State	Published - 2022
Externally published	Yes

ASJC Scopus Subject Areas

Food Science
Pharmacology

Keywords

Drug repurposing
Lansoprazole
Leishmaniasis
Molecular dynamics
Posaconazole

Access to Document

10.38212/2224-6614.3394

Cite this

Gupta, Y., Goicoechea, S., Romero, J. G., Mathur, R., Caulfield, T. R., Becker, D. P., Durvasula, R., & Kempaiah, P. (2022). Repurposing Lansoprazole and Posaconazole to treat leishmaniasis: Integration of in vitro testing, pharmacological corroboration, and mechanisms of action. Journal of Food and Drug Analysis, 30(1), 128-149. Article 11. https://doi.org/10.38212/2224-6614.3394

Gupta, Y, Goicoechea, S, Romero, JG, Mathur, R, Caulfield, TR, Becker, DP, Durvasula, R & Kempaiah, P 2022, 'Repurposing Lansoprazole and Posaconazole to treat leishmaniasis: Integration of in vitro testing, pharmacological corroboration, and mechanisms of action', Journal of Food and Drug Analysis, vol. 30, no. 1, 11, pp. 128-149. https://doi.org/10.38212/2224-6614.3394

@article{9afeea7978034c9fb454fcf7d7c0f639,

title = "Repurposing Lansoprazole and Posaconazole to treat leishmaniasis: Integration of in vitro testing, pharmacological corroboration, and mechanisms of action",

keywords = "Drug repurposing, Lansoprazole, Leishmaniasis, Molecular dynamics, Posaconazole",

author = "Yash Gupta and Steven Goicoechea and Romero, {Jesus G.} and Raman Mathur and Caulfield, {Thomas R.} and Becker, {Daniel P.} and Ravi Durvasula and Prakasha Kempaiah",

year = "2022",

doi = "10.38212/2224-6614.3394",

language = "English",

volume = "30",

pages = "128--149",

journal = "Journal of Food and Drug Analysis",

issn = "1021-9498",

number = "1",

}

TY - JOUR

T1 - Repurposing Lansoprazole and Posaconazole to treat leishmaniasis

T2 - Integration of in vitro testing, pharmacological corroboration, and mechanisms of action

AU - Gupta, Yash

AU - Goicoechea, Steven

AU - Romero, Jesus G.

AU - Mathur, Raman

AU - Caulfield, Thomas R.

AU - Becker, Daniel P.

AU - Durvasula, Ravi

AU - Kempaiah, Prakasha

PY - 2022

Y1 - 2022

KW - Drug repurposing

KW - Lansoprazole

KW - Leishmaniasis

KW - Molecular dynamics

KW - Posaconazole

UR - http://www.scopus.com/inward/record.url?scp=85127177417&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85127177417&partnerID=8YFLogxK

U2 - 10.38212/2224-6614.3394

DO - 10.38212/2224-6614.3394

M3 - Article

C2 - 35647721

AN - SCOPUS:85127177417

SN - 1021-9498

VL - 30

SP - 128

EP - 149

JO - Journal of Food and Drug Analysis

JF - Journal of Food and Drug Analysis

IS - 1

M1 - 11

ER -

Repurposing Lansoprazole and Posaconazole to treat leishmaniasis: Integration of in vitro testing, pharmacological corroboration, and mechanisms of action

ASJC Scopus Subject Areas

Keywords

Access to Document

Other files and links

Cite this