Quantum mechanical analysis of nonenzymatic nucleotidyl transfer reactions: kinetic and thermodynamic effects of β-γ bridging groups of dNTP substrates.

Zheng Zhang; Josh Eloge; Jan Florián; Jan Florian

doi:10.1021/bi5003713

Quantum mechanical analysis of nonenzymatic nucleotidyl transfer reactions: kinetic and thermodynamic effects of β-γ bridging groups of dNTP substrates.

Zheng Zhang
, Josh Eloge
, Jan Florián
, Jan Florian

Loyola University Chicago

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Biochemistry
Volume	53
Issue number	25
DOIs	https://doi.org/10.1021/bi5003713
State	Published - Jan 7 2014

Disciplines

Biochemistry

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title = "Quantum mechanical analysis of nonenzymatic nucleotidyl transfer reactions: kinetic and thermodynamic effects of β-γ bridging groups of dNTP substrates.",

author = "Zheng Zhang and Josh Eloge and Jan Flori{\'a}n and Jan Florian",

note = "Rate (k) and equilibrium (K) constants for the reaction of tetrahydrofuranol with a series of Mg[2+] complexes of methyl triphosphate analogues, CH[3] O-P(O[2] )-O-P(O[2] )-X-PO[3] [4-] , X = O, CH[2] , CHCH[3] , C(CH[3] )[2] , CFCH[3] , CHF, ...",

year = "2014",

month = jan,

day = "7",

doi = "10.1021/bi5003713",

language = "American English",

volume = "53",

journal = "Biochemistry",

number = "25",

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T1 - Quantum mechanical analysis of nonenzymatic nucleotidyl transfer reactions: kinetic and thermodynamic effects of β-γ bridging groups of dNTP substrates.

AU - Zhang, Zheng

AU - Eloge, Josh

AU - Florián, Jan

AU - Florian, Jan

N1 - Rate (k) and equilibrium (K) constants for the reaction of tetrahydrofuranol with a series of Mg[2+] complexes of methyl triphosphate analogues, CH[3] O-P(O[2] )-O-P(O[2] )-X-PO[3] [4-] , X = O, CH[2] , CHCH[3] , C(CH[3] )[2] , CFCH[3] , CHF, ...

PY - 2014/1/7

Y1 - 2014/1/7

UR - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081047/

U2 - 10.1021/bi5003713

DO - 10.1021/bi5003713

M3 - Article

VL - 53

JO - Biochemistry

JF - Biochemistry

IS - 25

ER -

Quantum mechanical analysis of nonenzymatic nucleotidyl transfer reactions: kinetic and thermodynamic effects of β-γ bridging groups of dNTP substrates.

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