Protein Phosphatase 2A Activation Via ApoER2 in Trophoblasts Drives Preeclampsia in a Mouse Model of the Antiphospholipid Syndrome

Haiyan Chu; Anastasia Sacharidou; An Nguyen; Chun Li; Ken L. Chambliss; Jane E. Salmon; Yu Min Shen; Julie Lo; Gustavo W. Leone; Joachim Herz; David Y. Hui; Denise K. Marciano; Vikki M. Abrahams; Bryony V. Natale; Alina P. Montalbano; Xue Xiao; Lin Xu; David R. Natale; Philip W. Shaul; Chieko Mineo

doi:10.1161/CIRCRESAHA.120.318941

Protein Phosphatase 2A Activation Via ApoER2 in Trophoblasts Drives Preeclampsia in a Mouse Model of the Antiphospholipid Syndrome

Haiyan Chu, Anastasia Sacharidou, An Nguyen, Chun Li, Ken L. Chambliss, Jane E. Salmon, Yu Min Shen, Julie Lo, Gustavo W. Leone, Joachim Herz, David Y. Hui, Denise K. Marciano, Vikki M. Abrahams, Bryony V. Natale, Alina P. Montalbano, Xue Xiao, Lin Xu, David R. Natale, Philip W. Shaul, Chieko Mineo

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	735-750
Number of pages	16
Journal	Circulation Research
Volume	129
Issue number	7
DOIs	https://doi.org/10.1161/CIRCRESAHA.120.318941
State	Published - Sep 17 2021
Externally published	Yes

ASJC Scopus Subject Areas

Physiology
Cardiology and Cardiovascular Medicine

Keywords

antiphospholipid syndrome
endoglin
placenta
preeclampsia
proteinuria
trophoblasts

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10.1161/CIRCRESAHA.120.318941

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Chu, H., Sacharidou, A., Nguyen, A., Li, C., Chambliss, K. L., Salmon, J. E., Shen, Y. M., Lo, J., Leone, G. W., Herz, J., Hui, D. Y., Marciano, D. K., Abrahams, V. M., Natale, B. V., Montalbano, A. P., Xiao, X., Xu, L., Natale, D. R., Shaul, P. W., & Mineo, C. (2021). Protein Phosphatase 2A Activation Via ApoER2 in Trophoblasts Drives Preeclampsia in a Mouse Model of the Antiphospholipid Syndrome. Circulation Research, 129(7), 735-750. https://doi.org/10.1161/CIRCRESAHA.120.318941

Chu, H, Sacharidou, A, Nguyen, A, Li, C, Chambliss, KL, Salmon, JE, Shen, YM, Lo, J, Leone, GW, Herz, J, Hui, DY, Marciano, DK, Abrahams, VM, Natale, BV, Montalbano, AP, Xiao, X, Xu, L, Natale, DR, Shaul, PW & Mineo, C 2021, 'Protein Phosphatase 2A Activation Via ApoER2 in Trophoblasts Drives Preeclampsia in a Mouse Model of the Antiphospholipid Syndrome', Circulation Research, vol. 129, no. 7, pp. 735-750. https://doi.org/10.1161/CIRCRESAHA.120.318941

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keywords = "antiphospholipid syndrome, endoglin, placenta, preeclampsia, proteinuria, trophoblasts",

author = "Haiyan Chu and Anastasia Sacharidou and An Nguyen and Chun Li and Chambliss, \{Ken L.\} and Salmon, \{Jane E.\} and Shen, \{Yu Min\} and Julie Lo and Leone, \{Gustavo W.\} and Joachim Herz and Hui, \{David Y.\} and Marciano, \{Denise K.\} and Abrahams, \{Vikki M.\} and Natale, \{Bryony V.\} and Montalbano, \{Alina P.\} and Xue Xiao and Lin Xu and Natale, \{David R.\} and Shaul, \{Philip W.\} and Chieko Mineo",

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doi = "10.1161/CIRCRESAHA.120.318941",

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T1 - Protein Phosphatase 2A Activation Via ApoER2 in Trophoblasts Drives Preeclampsia in a Mouse Model of the Antiphospholipid Syndrome

AU - Chu, Haiyan

AU - Sacharidou, Anastasia

AU - Nguyen, An

AU - Li, Chun

AU - Chambliss, Ken L.

AU - Salmon, Jane E.

AU - Shen, Yu Min

AU - Lo, Julie

AU - Leone, Gustavo W.

AU - Herz, Joachim

AU - Hui, David Y.

AU - Marciano, Denise K.

AU - Abrahams, Vikki M.

AU - Natale, Bryony V.

AU - Montalbano, Alina P.

AU - Xiao, Xue

AU - Xu, Lin

AU - Natale, David R.

AU - Shaul, Philip W.

AU - Mineo, Chieko

PY - 2021/9/17

Y1 - 2021/9/17

KW - antiphospholipid syndrome

KW - endoglin

KW - placenta

KW - preeclampsia

KW - proteinuria

KW - trophoblasts

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JO - Circulation Research

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ER -

Protein Phosphatase 2A Activation Via ApoER2 in Trophoblasts Drives Preeclampsia in a Mouse Model of the Antiphospholipid Syndrome

ASJC Scopus Subject Areas

Keywords

Access to Document

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