Phenylthiomethyl ketone-based fragments show selective and irreversible inhibition of enteroviral 3C proteases

Robert Schulz; Amira Atef; Daniel Becker; Franziska Gottschalk; Carolin Tauber; Stefan Wagner; Christoph Arkona; Atef A Abdel-Hafez; Hassan H Farag; Jörg Rademann; Gerhard Wolber

doi:10.1021/acs.jmedchem.7b01440

Phenylthiomethyl ketone-based fragments show selective and irreversible inhibition of enteroviral 3C proteases

Robert Schulz
, Amira Atef
, Daniel Becker
, Franziska Gottschalk
, Carolin Tauber
, Stefan Wagner
, Christoph Arkona
, Atef A Abdel-Hafez
, Hassan H Farag
, Jörg Rademann
, Gerhard Wolber

Department of Chemistry and Biochemistry

Free University of Berlin
University of Siegen
Assiut University

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Journal of Medicinal Chemistry
DOIs	https://doi.org/10.1021/acs.jmedchem.7b01440
State	Published - Jan 12 2018

Disciplines

Biochemistry
Chemistry

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10.1021/acs.jmedchem.7b01440License: Unspecified

Cite this

@article{9df0070866d34f8e8711a70eeecf5146,

title = "Phenylthiomethyl ketone-based fragments show selective and irreversible inhibition of enteroviral 3C proteases",

author = "Robert Schulz and Amira Atef and Daniel Becker and Franziska Gottschalk and Carolin Tauber and Stefan Wagner and Christoph Arkona and Abdel-Hafez, \{Atef A\} and Farag, \{Hassan H\} and J{\"o}rg Rademann and Gerhard Wolber",

year = "2018",

month = jan,

day = "12",

doi = "10.1021/acs.jmedchem.7b01440",

language = "American English",

journal = "Journal of Medicinal Chemistry",

}

TY - JOUR

T1 - Phenylthiomethyl ketone-based fragments show selective and irreversible inhibition of enteroviral 3C proteases

AU - Schulz, Robert

AU - Atef, Amira

AU - Becker, Daniel

AU - Gottschalk, Franziska

AU - Tauber, Carolin

AU - Wagner, Stefan

AU - Arkona, Christoph

AU - Abdel-Hafez, Atef A

AU - Farag, Hassan H

AU - Rademann, Jörg

AU - Wolber, Gerhard

PY - 2018/1/12

Y1 - 2018/1/12

UR - http://pubs.acs.org/doi/10.1021/acs.jmedchem.7b01440

U2 - 10.1021/acs.jmedchem.7b01440

DO - 10.1021/acs.jmedchem.7b01440

M3 - Article

JO - Journal of Medicinal Chemistry

JF - Journal of Medicinal Chemistry

ER -

Phenylthiomethyl ketone-based fragments show selective and irreversible inhibition of enteroviral 3C proteases

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