Necroptosis in spontaneously-mutated hematopoietic cells induces autoimmune bone marrow failure in mice

Junping Xin; Peter Breslin; Wei Wei; Jing Li; Rafael Gutierrez; Joseph Cannova; Allen Ni; Grace Ng; Rachel Schmidt; Haiyan Chen; Vamsi Parini; Paul C. Kuo; Ameet R. Kini; Patrick Stiff; Jiang Zhu; Jiwang Zhang

doi:10.3324/haematol.2016.151514

Necroptosis in spontaneously-mutated hematopoietic cells induces autoimmune bone marrow failure in mice

Junping Xin
, Peter Breslin
, Wei Wei
, Jing Li
, Rafael Gutierrez
, Joseph Cannova
, Allen Ni
, Grace Ng
, Rachel Schmidt
, Haiyan Chen
, Vamsi Parini
, Paul C. Kuo
, Ameet R. Kini
, Patrick Stiff
, Jiang Zhu
, Jiwang Zhang

Department of Biology

Loyola University Medical Center
Shanghai Normal University
Shanghai Jiao Tong University

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Haematologica
Volume	102
Issue number	2
DOIs	https://doi.org/10.3324/haematol.2016.151514
State	Published - Feb 1 2017

Disciplines

Biology
Immunology and Infectious Disease

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@article{91625035a6fd43e7871ee528a41d9db5,

title = "Necroptosis in spontaneously-mutated hematopoietic cells induces autoimmune bone marrow failure in mice",

author = "Junping Xin and Peter Breslin and Wei Wei and Jing Li and Rafael Gutierrez and Joseph Cannova and Allen Ni and Grace Ng and Rachel Schmidt and Haiyan Chen and Vamsi Parini and Kuo, \{Paul C.\} and Kini, \{Ameet R.\} and Patrick Stiff and Jiang Zhu and Jiwang Zhang",

note = "Acquired aplastic anemia is an autoimmune-mediated bone marrow failure syndrome. The mechanism by which such an autoimmune reaction is initiated is unknown. Whether and how the genetic lesions detected in patients cause autoimmune bone marrow failure have not yet been determined.",

year = "2017",

month = feb,

day = "1",

doi = "10.3324/haematol.2016.151514",

language = "American English",

volume = "102",

journal = "Haematologica",

number = "2",

}

TY - JOUR

T1 - Necroptosis in spontaneously-mutated hematopoietic cells induces autoimmune bone marrow failure in mice

AU - Xin, Junping

AU - Breslin, Peter

AU - Wei, Wei

AU - Li, Jing

AU - Gutierrez, Rafael

AU - Cannova, Joseph

AU - Ni, Allen

AU - Ng, Grace

AU - Schmidt, Rachel

AU - Chen, Haiyan

AU - Parini, Vamsi

AU - Kuo, Paul C.

AU - Kini, Ameet R.

AU - Stiff, Patrick

AU - Zhu, Jiang

AU - Zhang, Jiwang

N1 - Acquired aplastic anemia is an autoimmune-mediated bone marrow failure syndrome. The mechanism by which such an autoimmune reaction is initiated is unknown. Whether and how the genetic lesions detected in patients cause autoimmune bone marrow failure have not yet been determined.

PY - 2017/2/1

Y1 - 2017/2/1

UR - http://www.haematologica.org/content/102/2/295

U2 - 10.3324/haematol.2016.151514

DO - 10.3324/haematol.2016.151514

M3 - Article

VL - 102

JO - Haematologica

JF - Haematologica

IS - 2

ER -

Necroptosis in spontaneously-mutated hematopoietic cells induces autoimmune bone marrow failure in mice

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