Mechanism of Inactivation of GABA Aminotransferase by (E)- and (Z)-(1S,3S)-3-Amino-4-fluoromethylenyl-1-cyclopentanoic Acid

Hyunbeom Lee; Hoang V. Le; Rui Wu; Emma Doud; Ruslan Sanishvili; John F. Kellie; Phillip D. Compton; Boobalan Pachaiyappan; Dali Liu; Neil L. Kelleher; Richard B. Silverman

doi:10.1021/acschembio.5b00212

Mechanism of Inactivation of GABA Aminotransferase by (E)- and (Z)-(1S,3S)-3-Amino-4-fluoromethylenyl-1-cyclopentanoic Acid

Hyunbeom Lee, Hoang V. Le, Rui Wu, Emma Doud, Ruslan Sanishvili, John F. Kellie, Phillip D. Compton, Boobalan Pachaiyappan, Dali Liu, Neil L. Kelleher, Richard B. Silverman

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	2087-2098
Number of pages	12
Journal	ACS Chemical Biology
Volume	10
Issue number	9
DOIs	https://doi.org/10.1021/acschembio.5b00212
State	Published - Sep 18 2015
Externally published	Yes

ASJC Scopus Subject Areas

Biochemistry
Molecular Medicine

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10.1021/acschembio.5b00212

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@article{04c64d38854b49f7802ede9092aa876e,

title = "Mechanism of Inactivation of GABA Aminotransferase by (E)- and (Z)-(1S,3S)-3-Amino-4-fluoromethylenyl-1-cyclopentanoic Acid",

author = "Hyunbeom Lee and Le, {Hoang V.} and Rui Wu and Emma Doud and Ruslan Sanishvili and Kellie, {John F.} and Compton, {Phillip D.} and Boobalan Pachaiyappan and Dali Liu and Kelleher, {Neil L.} and Silverman, {Richard B.}",

note = "Publisher Copyright: {\textcopyright} 2015 American Chemical Society.",

year = "2015",

month = sep,

day = "18",

doi = "10.1021/acschembio.5b00212",

language = "English",

volume = "10",

pages = "2087--2098",

journal = "ACS Chemical Biology",

issn = "1554-8929",

number = "9",

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T1 - Mechanism of Inactivation of GABA Aminotransferase by (E)- and (Z)-(1S,3S)-3-Amino-4-fluoromethylenyl-1-cyclopentanoic Acid

AU - Lee, Hyunbeom

AU - Le, Hoang V.

AU - Wu, Rui

AU - Doud, Emma

AU - Sanishvili, Ruslan

AU - Kellie, John F.

AU - Compton, Phillip D.

AU - Pachaiyappan, Boobalan

AU - Liu, Dali

AU - Kelleher, Neil L.

AU - Silverman, Richard B.

PY - 2015/9/18

Y1 - 2015/9/18

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U2 - 10.1021/acschembio.5b00212

DO - 10.1021/acschembio.5b00212

M3 - Article

C2 - 26110556

AN - SCOPUS:84942049010

SN - 1554-8929

VL - 10

SP - 2087

EP - 2098

JO - ACS Chemical Biology

JF - ACS Chemical Biology

IS - 9

ER -

Mechanism of Inactivation of GABA Aminotransferase by (E)- and (Z)-(1S,3S)-3-Amino-4-fluoromethylenyl-1-cyclopentanoic Acid

ASJC Scopus Subject Areas

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