Mapping gastrointestinal gene expression patterns in wild primates and humans via fecal RNA-seq

Ashok Kumar Sharma; Barbora Pafčo; Klára Vlčková; Barbora Červená; Jakub Kreisinger; Samuel Davison; Karen Beeri; Terence Fuh; Steven R. Leigh; Michael B. Burns; Ran Blekhman; Klára J. Petrželková; Andres Gomez

doi:10.1186/s12864-019-5813-z

Mapping gastrointestinal gene expression patterns in wild primates and humans via fecal RNA-seq

Ashok Kumar Sharma
, Barbora Pafčo
, Klára Vlčková
, Barbora Červená
, Jakub Kreisinger
, Samuel Davison
, Karen Beeri
, Terence Fuh
, Steven R. Leigh
, Michael B. Burns
, Ran Blekhman
, Klára J. Petrželková
, Andres Gomez

Department of Biology

University of Minnesota
University of Veterinary and Pharmaceutical Sciences Brno
Charles University in Prague
Vanderbilt University Medical Center
WWF Central African Republic, Bangui, Central African Republic
University of Colorado Boulder
The Czech Academy of Sciences, Institute of Vertebrate Biology, Brno, Czech Republic

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	BMC Genomics
Volume	20
Issue number	1
DOIs	https://doi.org/10.1186/s12864-019-5813-z
State	Published - Dec 1 2019

Disciplines

Biology
Genetics

Access to Document

10.1186/s12864-019-5813-zLicense: Unspecified

Cite this

@article{36c63a6740984c6382cc8f436bf9fbda,

title = "Mapping gastrointestinal gene expression patterns in wild primates and humans via fecal RNA-seq",

author = "Sharma, \{Ashok Kumar\} and Barbora Paf{\v c}o and Kl{\'a}ra Vl{\v c}kov{\'a} and Barbora {\v C}erven{\'a} and Jakub Kreisinger and Samuel Davison and Karen Beeri and Terence Fuh and Leigh, \{Steven R.\} and Burns, \{Michael B.\} and Ran Blekhman and Petr{\v z}elkov{\'a}, \{Kl{\'a}ra J.\} and Andres Gomez",

note = "Limited accessibility to intestinal epithelial tissue in wild animals and humans makes it challenging to study patterns of intestinal gene regulation, and hence to monitor physiological status and health in field conditions. To explore solutions to this limitation, we have used a noninvasive approach via fecal RNA-seq, for the quantification of gene expression markers in gastrointestinal cells of free-range primates and a forager human population.",

year = "2019",

month = dec,

day = "1",

doi = "10.1186/s12864-019-5813-z",

language = "American English",

volume = "20",

journal = "BMC Genomics",

issn = "1471-2164",

number = "1",

}

TY - JOUR

T1 - Mapping gastrointestinal gene expression patterns in wild primates and humans via fecal RNA-seq

AU - Sharma, Ashok Kumar

AU - Pafčo, Barbora

AU - Vlčková, Klára

AU - Červená, Barbora

AU - Kreisinger, Jakub

AU - Davison, Samuel

AU - Beeri, Karen

AU - Fuh, Terence

AU - Leigh, Steven R.

AU - Burns, Michael B.

AU - Blekhman, Ran

AU - Petrželková, Klára J.

AU - Gomez, Andres

N1 - Limited accessibility to intestinal epithelial tissue in wild animals and humans makes it challenging to study patterns of intestinal gene regulation, and hence to monitor physiological status and health in field conditions. To explore solutions to this limitation, we have used a noninvasive approach via fecal RNA-seq, for the quantification of gene expression markers in gastrointestinal cells of free-range primates and a forager human population.

PY - 2019/12/1

Y1 - 2019/12/1

UR - https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-019-5813-z

U2 - 10.1186/s12864-019-5813-z

DO - 10.1186/s12864-019-5813-z

M3 - Article

SN - 1471-2164

VL - 20

JO - BMC Genomics

JF - BMC Genomics

IS - 1

ER -

Mapping gastrointestinal gene expression patterns in wild primates and humans via fecal RNA-seq

Disciplines

Access to Document

Other files and links

Cite this