Integration of cell line and clinical trial genome-wide analyses supports a polygenic architecture of paclitaxel-induced sensory peripheral neuropathy

Heather E. Wheeler; Eric R. Gamazon; Claudia Wing; Uchenna O. Njiaju; Chidiamara Njoku; Robert Michael Baldwin; Kouros Owzar; Chen Jiang; Dorothy Watson; Ivo Shterev; Michiaki Kubo; Hitoshi Zembutsu; Eric P. Winer; Clifford A. Hudis; Lawrence N. Shulman; Yusuke Nakamura; Mark J. Ratain; Deanna L. Kroetz; Nancy J. Cox; Mary Eileen Dolan

doi:10.1158/1078-0432.CCR-12-2618

Integration of cell line and clinical trial genome-wide analyses supports a polygenic architecture of paclitaxel-induced sensory peripheral neuropathy

Heather E. Wheeler
, Eric R. Gamazon
, Claudia Wing
, Uchenna O. Njiaju
, Chidiamara Njoku
, Robert Michael Baldwin
, Kouros Owzar
, Chen Jiang
, Dorothy Watson
, Ivo Shterev
, Michiaki Kubo
, Hitoshi Zembutsu
, Eric P. Winer
, Clifford A. Hudis
, Lawrence N. Shulman
, Yusuke Nakamura
, Mark J. Ratain
, Deanna L. Kroetz
, Nancy J. Cox
, Mary Eileen Dolan

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	491-499
Number of pages	9
Journal	Clinical Cancer Research
Volume	19
Issue number	2
DOIs	https://doi.org/10.1158/1078-0432.CCR-12-2618
State	Published - Jan 15 2013
Externally published	Yes

ASJC Scopus Subject Areas

General Medicine

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10.1158/1078-0432.CCR-12-2618

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Wheeler, H. E., Gamazon, E. R., Wing, C., Njiaju, U. O., Njoku, C., Baldwin, R. M., Owzar, K., Jiang, C., Watson, D., Shterev, I., Kubo, M., Zembutsu, H., Winer, E. P., Hudis, C. A., Shulman, L. N., Nakamura, Y., Ratain, M. J., Kroetz, D. L., Cox, N. J., & Dolan, M. E. (2013). Integration of cell line and clinical trial genome-wide analyses supports a polygenic architecture of paclitaxel-induced sensory peripheral neuropathy. Clinical Cancer Research, 19(2), 491-499. https://doi.org/10.1158/1078-0432.CCR-12-2618

Wheeler, HE, Gamazon, ER, Wing, C, Njiaju, UO, Njoku, C, Baldwin, RM, Owzar, K, Jiang, C, Watson, D, Shterev, I, Kubo, M, Zembutsu, H, Winer, EP, Hudis, CA, Shulman, LN, Nakamura, Y, Ratain, MJ, Kroetz, DL, Cox, NJ & Dolan, ME 2013, 'Integration of cell line and clinical trial genome-wide analyses supports a polygenic architecture of paclitaxel-induced sensory peripheral neuropathy', Clinical Cancer Research, vol. 19, no. 2, pp. 491-499. https://doi.org/10.1158/1078-0432.CCR-12-2618

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title = "Integration of cell line and clinical trial genome-wide analyses supports a polygenic architecture of paclitaxel-induced sensory peripheral neuropathy",

author = "Wheeler, \{Heather E.\} and Gamazon, \{Eric R.\} and Claudia Wing and Njiaju, \{Uchenna O.\} and Chidiamara Njoku and Baldwin, \{Robert Michael\} and Kouros Owzar and Chen Jiang and Dorothy Watson and Ivo Shterev and Michiaki Kubo and Hitoshi Zembutsu and Winer, \{Eric P.\} and Hudis, \{Clifford A.\} and Shulman, \{Lawrence N.\} and Yusuke Nakamura and Ratain, \{Mark J.\} and Kroetz, \{Deanna L.\} and Cox, \{Nancy J.\} and Dolan, \{Mary Eileen\}",

year = "2013",

month = jan,

day = "15",

doi = "10.1158/1078-0432.CCR-12-2618",

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T1 - Integration of cell line and clinical trial genome-wide analyses supports a polygenic architecture of paclitaxel-induced sensory peripheral neuropathy

AU - Wheeler, Heather E.

AU - Gamazon, Eric R.

AU - Wing, Claudia

AU - Njiaju, Uchenna O.

AU - Njoku, Chidiamara

AU - Baldwin, Robert Michael

AU - Owzar, Kouros

AU - Jiang, Chen

AU - Watson, Dorothy

AU - Shterev, Ivo

AU - Kubo, Michiaki

AU - Zembutsu, Hitoshi

AU - Winer, Eric P.

AU - Hudis, Clifford A.

AU - Shulman, Lawrence N.

AU - Nakamura, Yusuke

AU - Ratain, Mark J.

AU - Kroetz, Deanna L.

AU - Cox, Nancy J.

AU - Dolan, Mary Eileen

PY - 2013/1/15

Y1 - 2013/1/15

UR - https://www.scopus.com/pages/publications/84872549256

UR - https://www.scopus.com/pages/publications/84872549256#tab=citedBy

U2 - 10.1158/1078-0432.CCR-12-2618

DO - 10.1158/1078-0432.CCR-12-2618

M3 - Article

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AN - SCOPUS:84872549256

SN - 1078-0432

VL - 19

SP - 491

EP - 499

JO - Clinical Cancer Research

JF - Clinical Cancer Research

IS - 2

ER -

Integration of cell line and clinical trial genome-wide analyses supports a polygenic architecture of paclitaxel-induced sensory peripheral neuropathy

ASJC Scopus Subject Areas

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