Genetic correlations between cartilage regeneration and degeneration reveal an inverse relationship

Muhammad Farooq Rai; James M. Cheverud; Eric J. Schmidt; Linda J. Sandell

doi:10.1016/J.JOCA.2020.04.013

Genetic correlations between cartilage regeneration and degeneration reveal an inverse relationship

Muhammad Farooq Rai
, James M. Cheverud
, Eric J. Schmidt
, Linda J. Sandell

Department of Biology

Washington University in St. Louis
College of Health Sciences, Bahrain

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Osteoarthritis and Cartilage
Volume	28
Issue number	8
DOIs	https://doi.org/10.1016/J.JOCA.2020.04.013
State	Published - Aug 1 2020

Disciplines

Biology
Internal Medicine
Endocrinology

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10.1016/J.JOCA.2020.04.013License: Unspecified

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@article{c58e10d696284589a1e6d347466f0268,

title = "Genetic correlations between cartilage regeneration and degeneration reveal an inverse relationship",

author = "Rai, \{Muhammad Farooq\} and Cheverud, \{James M.\} and Schmidt, \{Eric J.\} and Sandell, \{Linda J.\}",

note = "Objective: The etiology of osteoarthritis (OA) is unknown, however, there appears to be a significant contribution from genetics. We have identified recombinant inbred strains of mice derived from LG/J (large) and SM/J (small) strains that vary significantly in their ability to repair articular cartilage and susceptibility to post-traumatic OA due to their genetic composition.",

year = "2020",

month = aug,

day = "1",

doi = "10.1016/J.JOCA.2020.04.013",

language = "American English",

volume = "28",

journal = "Osteoarthritis and Cartilage",

issn = "1522-9653",

number = "8",

}

TY - JOUR

T1 - Genetic correlations between cartilage regeneration and degeneration reveal an inverse relationship

AU - Rai, Muhammad Farooq

AU - Cheverud, James M.

AU - Schmidt, Eric J.

AU - Sandell, Linda J.

N1 - Objective: The etiology of osteoarthritis (OA) is unknown, however, there appears to be a significant contribution from genetics. We have identified recombinant inbred strains of mice derived from LG/J (large) and SM/J (small) strains that vary significantly in their ability to repair articular cartilage and susceptibility to post-traumatic OA due to their genetic composition.

PY - 2020/8/1

Y1 - 2020/8/1

UR - https://profiles.wustl.edu/en/publications/genetic-correlations-between-cartilage-regeneration-and-degenerat

U2 - 10.1016/J.JOCA.2020.04.013

DO - 10.1016/J.JOCA.2020.04.013

M3 - Article

SN - 1522-9653

VL - 28

JO - Osteoarthritis and Cartilage

JF - Osteoarthritis and Cartilage

IS - 8

ER -

Genetic correlations between cartilage regeneration and degeneration reveal an inverse relationship

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