DNA Polymerase λ Active Site Favors a Mutagenic Mispair between the Enol Form of Deoxyguanosine Triphosphate Substrate and the Keto Form of Thymidine Template: A Free Energy Perturbation Study

Sergey N. Maximoff; Shina Caroline Lynn Kamerlin; Jan Florián; Jan Florian

doi:10.1021/acs.jpcb.7b04874

DNA Polymerase λ Active Site Favors a Mutagenic Mispair between the Enol Form of Deoxyguanosine Triphosphate Substrate and the Keto Form of Thymidine Template: A Free Energy Perturbation Study

Sergey N. Maximoff
, Shina Caroline Lynn Kamerlin
, Jan Florián
, Jan Florian

Uppsala University
Loyola University Chicago

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Journal of Physical Chemistry B
Volume	121
Issue number	33
DOIs	https://doi.org/10.1021/acs.jpcb.7b04874
State	Published - Aug 24 2017

Disciplines

Biochemistry
Chemistry

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10.1021/acs.jpcb.7b04874License: Unspecified

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DNA Polymerase λ Active Site Favors a Mutagenic Mispair between the Enol Form of Deoxyguanosine Triphosphate Substrate and the Keto Form of Thymidine Template: A Free Energy Perturbation Study. / Maximoff, Sergey N.; Kamerlin, Shina Caroline Lynn; Florián, Jan et al.
In: Journal of Physical Chemistry B, Vol. 121, No. 33, 24.08.2017.

Research output: Contribution to journal › Article › peer-review

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title = "DNA Polymerase λ Active Site Favors a Mutagenic Mispair between the Enol Form of Deoxyguanosine Triphosphate Substrate and the Keto Form of Thymidine Template: A Free Energy Perturbation Study",

author = "Maximoff, \{Sergey N.\} and Kamerlin, \{Shina Caroline Lynn\} and Jan Flori{\'a}n and Jan Florian",

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language = "American English",

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AU - Maximoff, Sergey N.

AU - Kamerlin, Shina Caroline Lynn

AU - Florián, Jan

AU - Florian, Jan

PY - 2017/8/24

Y1 - 2017/8/24

UR - http://pubs.acs.org/doi/10.1021/acs.jpcb.7b04874

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DO - 10.1021/acs.jpcb.7b04874

M3 - Article

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VL - 121

JO - Journal of Physical Chemistry B

JF - Journal of Physical Chemistry B

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ER -

DNA Polymerase λ Active Site Favors a Mutagenic Mispair between the Enol Form of Deoxyguanosine Triphosphate Substrate and the Keto Form of Thymidine Template: A Free Energy Perturbation Study

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