DNA Polymerase β Fidelity: Halomethylene-Modified Leaving Groups in Pre-Steady-State Kinetic Analysis Reveal Differences at the Chemical Transition State†

Christopher A. Sucato; Thomas G. Upton; Boris A. Kashemirov; Jorge Osuna; Keriann Oertell; William A. Beard; Samuel H. Wilson; Jan Florian; Arieh Warshel; Charles E. McKenna; Myron F. Goodman

doi:10.1021/bi7014162

DNA Polymerase β Fidelity: Halomethylene-Modified Leaving Groups in Pre-Steady-State Kinetic Analysis Reveal Differences at the Chemical Transition State†

Christopher A. Sucato
, Thomas G. Upton
, Boris A. Kashemirov
, Jorge Osuna
, Keriann Oertell
, William A. Beard
, Samuel H. Wilson
, Jan Florian
, Arieh Warshel
, Charles E. McKenna
, Myron F. Goodman

Department of Chemistry and Biochemistry

University of Southern California
National Institutes of Health

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Biochemistry
Volume	47
Issue number	3
DOIs	https://doi.org/10.1021/bi7014162
State	Published - Jan 1 2008

Disciplines

Biochemistry

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10.1021/bi7014162License: Unspecified

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Sucato, C. A., Upton, T. G., Kashemirov, B. A., Osuna, J., Oertell, K., Beard, W. A., Wilson, S. H., Florian, J., Warshel, A., McKenna, C. E., & Goodman, M. F. (2008). DNA Polymerase β Fidelity: Halomethylene-Modified Leaving Groups in Pre-Steady-State Kinetic Analysis Reveal Differences at the Chemical Transition State†. Biochemistry, 47(3). https://doi.org/10.1021/bi7014162

@article{c009373c6d264bb58f4750adec221dc2,

title = "DNA Polymerase β Fidelity: Halomethylene-Modified Leaving Groups in Pre-Steady-State Kinetic Analysis Reveal Differences at the Chemical Transition State†",

author = "Sucato, \{Christopher A.\} and Upton, \{Thomas G.\} and Kashemirov, \{Boris A.\} and Jorge Osuna and Keriann Oertell and Beard, \{William A.\} and Wilson, \{Samuel H.\} and Jan Florian and Arieh Warshel and McKenna, \{Charles E.\} and Goodman, \{Myron F.\}",

note = "Biochemistry. 2008 Jan 22;47(3):870-9. Epub 2007 Dec 28. Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural",

year = "2008",

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doi = "10.1021/bi7014162",

language = "American English",

volume = "47",

journal = "Biochemistry",

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T1 - DNA Polymerase β Fidelity: Halomethylene-Modified Leaving Groups in Pre-Steady-State Kinetic Analysis Reveal Differences at the Chemical Transition State†

AU - Sucato, Christopher A.

AU - Upton, Thomas G.

AU - Kashemirov, Boris A.

AU - Osuna, Jorge

AU - Oertell, Keriann

AU - Beard, William A.

AU - Wilson, Samuel H.

AU - Florian, Jan

AU - Warshel, Arieh

AU - McKenna, Charles E.

AU - Goodman, Myron F.

N1 - Biochemistry. 2008 Jan 22;47(3):870-9. Epub 2007 Dec 28. Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural

PY - 2008/1/1

Y1 - 2008/1/1

UR - https://www.ncbi.nlm.nih.gov/pubmed/18161950

U2 - 10.1021/bi7014162

DO - 10.1021/bi7014162

M3 - Article

VL - 47

JO - Biochemistry

JF - Biochemistry

IS - 3

ER -

DNA Polymerase β Fidelity: Halomethylene-Modified Leaving Groups in Pre-Steady-State Kinetic Analysis Reveal Differences at the Chemical Transition State†

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Access to Document

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