DNA Polymerase β Fidelity: Halomethylene-Modified Leaving Groups in Pre-Steady-State Kinetic Analysis Reveal Differences at the Chemical Transition State†

Christopher A. Sucato; Thomas G. Upton; Boris A. Kashemirov; Jorge Osuna; Keriann Oertell; William A. Beard; Samuel H. Wilson; Jan Florian; Arieh Warshel; Charles E. McKenna; Myron F. Goodman

doi:10.1021/bi7014162

DNA Polymerase β Fidelity: Halomethylene-Modified Leaving Groups in Pre-Steady-State Kinetic Analysis Reveal Differences at the Chemical Transition State†

Christopher A. Sucato, Thomas G. Upton, Boris A. Kashemirov, Jorge Osuna, Keriann Oertell, William A. Beard, Samuel H. Wilson, Jan Florian, Arieh Warshel, Charles E. McKenna, Myron F. Goodman

Department of Chemistry and Biochemistry

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Biochemistry
Volume	47
Issue number	3
DOIs	https://doi.org/10.1021/bi7014162
State	Published - Jan 1 2008

Disciplines

Biochemistry

Access to Document

10.1021/bi7014162License: Unspecified

Cite this

Sucato, C. A., Upton, T. G., Kashemirov, B. A., Osuna, J., Oertell, K., Beard, W. A., Wilson, S. H., Florian, J., Warshel, A., McKenna, C. E., & Goodman, M. F. (2008). DNA Polymerase β Fidelity: Halomethylene-Modified Leaving Groups in Pre-Steady-State Kinetic Analysis Reveal Differences at the Chemical Transition State†. Biochemistry, 47(3). https://doi.org/10.1021/bi7014162

@article{c009373c6d264bb58f4750adec221dc2,

title = "DNA Polymerase β Fidelity: Halomethylene-Modified Leaving Groups in Pre-Steady-State Kinetic Analysis Reveal Differences at the Chemical Transition State†",

author = "Sucato, {Christopher A.} and Upton, {Thomas G.} and Kashemirov, {Boris A.} and Jorge Osuna and Keriann Oertell and Beard, {William A.} and Wilson, {Samuel H.} and Jan Florian and Arieh Warshel and McKenna, {Charles E.} and Goodman, {Myron F.}",

note = "Biochemistry. 2008 Jan 22;47(3):870-9. Epub 2007 Dec 28. Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural",

year = "2008",

month = jan,

day = "1",

doi = "10.1021/bi7014162",

language = "American English",

volume = "47",

journal = "Biochemistry",

number = "3",

}

TY - JOUR

T1 - DNA Polymerase β Fidelity: Halomethylene-Modified Leaving Groups in Pre-Steady-State Kinetic Analysis Reveal Differences at the Chemical Transition State†

AU - Sucato, Christopher A.

AU - Upton, Thomas G.

AU - Kashemirov, Boris A.

AU - Osuna, Jorge

AU - Oertell, Keriann

AU - Beard, William A.

AU - Wilson, Samuel H.

AU - Florian, Jan

AU - Warshel, Arieh

AU - McKenna, Charles E.

AU - Goodman, Myron F.

N1 - Biochemistry. 2008 Jan 22;47(3):870-9. Epub 2007 Dec 28. Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural

PY - 2008/1/1

Y1 - 2008/1/1

UR - https://www.ncbi.nlm.nih.gov/pubmed/18161950

U2 - 10.1021/bi7014162

DO - 10.1021/bi7014162

M3 - Article

VL - 47

JO - Biochemistry

JF - Biochemistry

IS - 3

ER -

DNA Polymerase β Fidelity: Halomethylene-Modified Leaving Groups in Pre-Steady-State Kinetic Analysis Reveal Differences at the Chemical Transition State†

Disciplines

Access to Document

Other files and links

Cite this