Cyclobutanone Inhibitors of Diaminopimelate Desuccinylase (DapE) as Potential New Antibiotics

Thahani S. Habeeb Mohammad, Emma H. Kelley, Cory T. Reidl, Katherine Konczak, Megan Beulke, Janielle Javier, Kenneth W. Olsen, Daniel P. Becker

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Article number1339
JournalInternational Journal of Molecular Sciences
Volume25
Issue number2
DOIs
StatePublished - Jan 2024
Externally publishedYes

ASJC Scopus Subject Areas

  • Catalysis
  • Molecular Biology
  • Spectroscopy
  • Computer Science Applications
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

Keywords

  • antibiotic
  • cyclobutanone
  • DapE
  • diaminopimelate desuccinylase
  • docking
  • enzyme inhibitor
  • molecular modeling
  • peptidomimetic

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