Computer simulation studies of the fidelity of DNA polymerases

Jan Florián, Myron F. Goodman, Arieh Warshel

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)286-299
Number of pages14
JournalBiopolymers
Volume68
Issue number3
DOIs
StatePublished - Mar 2003
Externally publishedYes

ASJC Scopus Subject Areas

  • Biophysics
  • Biochemistry
  • Biomaterials
  • Organic Chemistry

Keywords

  • Computer simulations
  • DNA polymerases
  • Empirical valence bond
  • Free energy perturbation
  • Linear response approximation
  • Mismatched base pairs
  • Replication fidelity

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