Bioisosteric replacement of pyridoxal-5′-phosphate to pyridoxal-5′-tetrazole targeting Bacillus subtilis GabR

Nicholas E. Kaley, Zachary J. Liveris, Maxwell Moore, Cory T. Reidl, Zdzislaw Wawrzak, Daniel P. Becker, Dali Liu

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Article numbere70014
JournalProtein Science
Volume34
Issue number1
DOIs
StatePublished - Jan 2025
Externally publishedYes

ASJC Scopus Subject Areas

  • Biochemistry
  • Molecular Biology

Keywords

  • antibiotic
  • bioisosterism
  • external aldimine
  • GabR
  • internal aldimine
  • pyridoxal-5'-phosphate
  • tetrazole

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