Abstract
The oxidation of ketones by a chiral bimetallic palladium(II) complex in the presence of CuCl2 in THF–water solvents gave an enantioselective synthesis of α-hydroxyketones in catalytic oxidation utilizing an atmosphere of oxygen. The ee’s ranged from 61% to 92%. The reaction was accelerated by addition of strong acid that presumably increases the rate of enolization.
Original language | American English |
---|---|
Journal | ChemInform |
Volume | 43 |
Issue number | 36 |
DOIs | |
State | Published - Sep 4 2012 |
Keywords
- ketone
- oxidation
- bimetallic
- palladium(II) complex
Disciplines
- Polymer Chemistry