An Analytical Method for Detecting Toxic Metal Cations Using Cyclotriveratrylene Derivative Capped Gold Nanoparticles

Zachary R. Osner; Richard C Holz; Daniel P Becker

doi:10.1016/j.tetlet.2015.08.005

An Analytical Method for Detecting Toxic Metal Cations Using Cyclotriveratrylene Derivative Capped Gold Nanoparticles

Zachary R. Osner, Richard C Holz, Daniel P Becker

Department of Chemistry and Biochemistry

Research output: Contribution to journal › Article › peer-review

Abstract

Cyclotriveratrylene-oxime (CTV-oxime) derivatives that terminate with a dithiolate linker were synthesized enabling the supramolecular scaffold to adhere to gold nanoparticles (AuNPs) with the bowl-shaped cavity of the CTV scaffold exposed for utilization in host–guest chemistry. Exposure of these CTV functionalized AuNPs to varying concentrations of di- and trivalent metal cations resulted in the formation of large CTV-AuNP polymeric clusters and an accompanying a shift in the plasmon resonance. These interactions between the CTV-AuNPs and the metal cations in solution provides proof-of-concept that supramolecular functionalized AuNPs can be used as a simple and straightforward, on-site detection system for toxic metal cations in solution. The order of binding affinity of the metals studied based on observed K _d values is Cu ²⁺ > Zn ²⁺ > Pb ²⁺ > Hg ²⁺ > Eu ³⁺ > Cd ²⁺ .

Original language	American English
Journal	Chemistry: Faculty Publications and Other Works
Volume	56
Issue number	40
DOIs	https://doi.org/10.1016/j.tetlet.2015.08.005
State	Published - Sep 1 2015

Keywords

Gold Nanoparticles
Supramolecular Chemistry
Heavy Metal Detection
Lanthanides
Cyclotriveratrylene

Disciplines

Biochemistry
Chemistry

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title = "An Analytical Method for Detecting Toxic Metal Cations Using Cyclotriveratrylene Derivative Capped Gold Nanoparticles",

abstract = " Cyclotriveratrylene-oxime (CTV-oxime) derivatives that terminate with a dithiolate linker were synthesized enabling the supramolecular scaffold to adhere to gold nanoparticles (AuNPs) with the bowl-shaped cavity of the CTV scaffold exposed for utilization in host–guest chemistry. Exposure of these CTV functionalized AuNPs to varying concentrations of di- and trivalent metal cations resulted in the formation of large CTV-AuNP polymeric clusters and an accompanying a shift in the plasmon resonance. These interactions between the CTV-AuNPs and the metal cations in solution provides proof-of-concept that supramolecular functionalized AuNPs can be used as a simple and straightforward, on-site detection system for toxic metal cations in solution. The order of binding affinity of the metals studied based on observed K d values is Cu 2+ > Zn 2+ > Pb 2+ > Hg 2+ > Eu 3+ > Cd 2+ .",

keywords = "Gold Nanoparticles, Supramolecular Chemistry, Heavy Metal Detection, Lanthanides, Cyclotriveratrylene",

author = "Osner, {Zachary R.} and Holz, {Richard C} and Becker, {Daniel P}",

year = "2015",

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doi = "10.1016/j.tetlet.2015.08.005",

language = "American English",

volume = "56",

journal = "Chemistry: Faculty Publications and Other Works",

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T1 - An Analytical Method for Detecting Toxic Metal Cations Using Cyclotriveratrylene Derivative Capped Gold Nanoparticles

AU - Osner, Zachary R.

AU - Holz, Richard C

AU - Becker, Daniel P

PY - 2015/9/1

Y1 - 2015/9/1

N2 - Cyclotriveratrylene-oxime (CTV-oxime) derivatives that terminate with a dithiolate linker were synthesized enabling the supramolecular scaffold to adhere to gold nanoparticles (AuNPs) with the bowl-shaped cavity of the CTV scaffold exposed for utilization in host–guest chemistry. Exposure of these CTV functionalized AuNPs to varying concentrations of di- and trivalent metal cations resulted in the formation of large CTV-AuNP polymeric clusters and an accompanying a shift in the plasmon resonance. These interactions between the CTV-AuNPs and the metal cations in solution provides proof-of-concept that supramolecular functionalized AuNPs can be used as a simple and straightforward, on-site detection system for toxic metal cations in solution. The order of binding affinity of the metals studied based on observed K d values is Cu 2+ > Zn 2+ > Pb 2+ > Hg 2+ > Eu 3+ > Cd 2+ .

AB - Cyclotriveratrylene-oxime (CTV-oxime) derivatives that terminate with a dithiolate linker were synthesized enabling the supramolecular scaffold to adhere to gold nanoparticles (AuNPs) with the bowl-shaped cavity of the CTV scaffold exposed for utilization in host–guest chemistry. Exposure of these CTV functionalized AuNPs to varying concentrations of di- and trivalent metal cations resulted in the formation of large CTV-AuNP polymeric clusters and an accompanying a shift in the plasmon resonance. These interactions between the CTV-AuNPs and the metal cations in solution provides proof-of-concept that supramolecular functionalized AuNPs can be used as a simple and straightforward, on-site detection system for toxic metal cations in solution. The order of binding affinity of the metals studied based on observed K d values is Cu 2+ > Zn 2+ > Pb 2+ > Hg 2+ > Eu 3+ > Cd 2+ .

KW - Gold Nanoparticles

KW - Supramolecular Chemistry

KW - Heavy Metal Detection

KW - Lanthanides

KW - Cyclotriveratrylene

UR - https://ecommons.luc.edu/chemistry_facpubs/87

U2 - 10.1016/j.tetlet.2015.08.005

DO - 10.1016/j.tetlet.2015.08.005

M3 - Article

VL - 56

JO - Chemistry: Faculty Publications and Other Works

JF - Chemistry: Faculty Publications and Other Works

IS - 40

ER -

An Analytical Method for Detecting Toxic Metal Cations Using Cyclotriveratrylene Derivative Capped Gold Nanoparticles

Abstract

Keywords

Disciplines

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