α,β-Methylene-2′-deoxynucleoside 5′-triphosphates as noncleavable substrates for DNA polymerases: Isolation, characterization, and stability studies of novel 2′-deoxycyclonucleosides, 3,5′-cyclo-dG, and 2,5′-cyclo-dT

Fengting Liang; Nidhi Jain; Troy Hutchens; David D. Shock; William A. Beard; Samuel H. Wilson; M. Paul Chiarelli; Bongsup P. Cho

doi:10.1021/jm800692a

α,β-Methylene-2′-deoxynucleoside 5′-triphosphates as noncleavable substrates for DNA polymerases: Isolation, characterization, and stability studies of novel 2′-deoxycyclonucleosides, 3,5′-cyclo-dG, and 2,5′-cyclo-dT

Fengting Liang, Nidhi Jain, Troy Hutchens, David D. Shock, William A. Beard, Samuel H. Wilson, M. Paul Chiarelli, Bongsup P. Cho

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	6460-6470
Number of pages	11
Journal	Journal of Medicinal Chemistry
Volume	51
Issue number	20
DOIs	https://doi.org/10.1021/jm800692a
State	Published - Oct 23 2008
Externally published	Yes

ASJC Scopus Subject Areas

Molecular Medicine
Drug Discovery

Access to Document

10.1021/jm800692a

Cite this

Liang, F., Jain, N., Hutchens, T., Shock, D. D., Beard, W. A., Wilson, S. H., Chiarelli, M. P., & Cho, B. P. (2008). α,β-Methylene-2′-deoxynucleoside 5′-triphosphates as noncleavable substrates for DNA polymerases: Isolation, characterization, and stability studies of novel 2′-deoxycyclonucleosides, 3,5′-cyclo-dG, and 2,5′-cyclo-dT. Journal of Medicinal Chemistry, 51(20), 6460-6470. https://doi.org/10.1021/jm800692a

α,β-Methylene-2′-deoxynucleoside 5′-triphosphates as noncleavable substrates for DNA polymerases: Isolation, characterization, and stability studies of novel 2′-deoxycyclonucleosides, 3,5′-cyclo-dG, and 2,5′-cyclo-dT. / Liang, Fengting; Jain, Nidhi; Hutchens, Troy et al.
In: Journal of Medicinal Chemistry, Vol. 51, No. 20, 23.10.2008, p. 6460-6470.

Research output: Contribution to journal › Article › peer-review

Liang, F, Jain, N, Hutchens, T, Shock, DD, Beard, WA, Wilson, SH, Chiarelli, MP & Cho, BP 2008, 'α,β-Methylene-2′-deoxynucleoside 5′-triphosphates as noncleavable substrates for DNA polymerases: Isolation, characterization, and stability studies of novel 2′-deoxycyclonucleosides, 3,5′-cyclo-dG, and 2,5′-cyclo-dT', Journal of Medicinal Chemistry, vol. 51, no. 20, pp. 6460-6470. https://doi.org/10.1021/jm800692a

Liang F, Jain N, Hutchens T, Shock DD, Beard WA, Wilson SH et al. α,β-Methylene-2′-deoxynucleoside 5′-triphosphates as noncleavable substrates for DNA polymerases: Isolation, characterization, and stability studies of novel 2′-deoxycyclonucleosides, 3,5′-cyclo-dG, and 2,5′-cyclo-dT. Journal of Medicinal Chemistry. 2008 Oct 23;51(20):6460-6470. doi: 10.1021/jm800692a

@article{7451e0a753744196989ec1217e0970c3,

title = "α,β-Methylene-2′-deoxynucleoside 5′-triphosphates as noncleavable substrates for DNA polymerases: Isolation, characterization, and stability studies of novel 2′-deoxycyclonucleosides, 3,5′-cyclo-dG, and 2,5′-cyclo-dT",

author = "Fengting Liang and Nidhi Jain and Troy Hutchens and Shock, \{David D.\} and Beard, \{William A.\} and Wilson, \{Samuel H.\} and Chiarelli, \{M. Paul\} and Cho, \{Bongsup P.\}",

year = "2008",

month = oct,

day = "23",

doi = "10.1021/jm800692a",

language = "English",

volume = "51",

pages = "6460--6470",

journal = "Journal of Medicinal Chemistry",

issn = "0022-2623",

number = "20",

}

TY - JOUR

T1 - α,β-Methylene-2′-deoxynucleoside 5′-triphosphates as noncleavable substrates for DNA polymerases

T2 - Isolation, characterization, and stability studies of novel 2′-deoxycyclonucleosides, 3,5′-cyclo-dG, and 2,5′-cyclo-dT

AU - Liang, Fengting

AU - Jain, Nidhi

AU - Hutchens, Troy

AU - Shock, David D.

AU - Beard, William A.

AU - Wilson, Samuel H.

AU - Chiarelli, M. Paul

AU - Cho, Bongsup P.

PY - 2008/10/23

Y1 - 2008/10/23

UR - https://www.scopus.com/pages/publications/54549127323

UR - https://www.scopus.com/inward/citedby.url?scp=54549127323&partnerID=8YFLogxK

U2 - 10.1021/jm800692a

DO - 10.1021/jm800692a

M3 - Article

C2 - 18811136

AN - SCOPUS:54549127323

SN - 0022-2623

VL - 51

SP - 6460

EP - 6470

JO - Journal of Medicinal Chemistry

JF - Journal of Medicinal Chemistry

IS - 20

ER -

α,β-Methylene-2′-deoxynucleoside 5′-triphosphates as noncleavable substrates for DNA polymerases: Isolation, characterization, and stability studies of novel 2′-deoxycyclonucleosides, 3,5′-cyclo-dG, and 2,5′-cyclo-dT

ASJC Scopus Subject Areas

Access to Document

Other files and links

Cite this